Mixed sclerosing bone dysplasia

Last revised by Francis Fortin on 10 Sep 2020

Citation, DOI, disclosures and article data

Citation:

Hacking C, Fortin F, Mixed sclerosing bone dysplasia. Reference article, Radiopaedia.org (Accessed on 19 Apr 2024) https://doi.org/10.53347/rID-69894

DOI:

https://doi.org/10.53347/rID-69894

Permalink:

https://radiopaedia.org/articles/69894?iframe=true

rID:

69894

Article created:

25 Jul 2019, Craig Hacking ◉ ◈

Disclosures:

At the time the article was created Craig Hacking had no recorded disclosures.

View Craig Hacking's current disclosures

Last revised:

10 Sep 2020, Francis Fortin

Disclosures:

At the time the article was last revised Francis Fortin had no recorded disclosures.

View Francis Fortin's current disclosures

Revisions:

2 times, by 2 contributors - see full revision history and disclosures

Systems:

Musculoskeletal

Synonyms:

MSBD

Mixed sclerosing bone dysplasia (MSBD) is a combined and highly variable bone sclerosing spectrum with shared features of 3 radiological entities:

Some authors propose these 3 conditions are within the same sclerosing spectrum ⁵. Little is known about this overlap dysplasia, which is proposed to be due to abnormal endochondral and intramembranous ossification. It may share an underlying etiology and loss of function mutations in the LEMD3 gene has been proposed ⁶.

It has features of all 3 components but is highly variable and its etiology may be inherited or sporadic.

References

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