Modic type endplate changes

Dr Daniel J Bell and Radswiki et al.

Modic type endplate changes represent a classification for vertebral body end-plate MRI signal, first described in 1988 1. It is widely recognized by radiologists and clinicians and is a useful shorthand for reporting MRIs of the spine.

Recently Modic type I has received renewed attention due to the possibility of it representing low grade indolent infection. It is thus discussed separately here.

  • Modic type I
    • T1: low signal
    • T2: high signal
    • represents bone marrow edema and inflammation
    • T1+C: enhancement
  • Modic type II
    • T1: high signal
    • T2: iso to high signal
    • represents normal red haemopoietic bone marrow conversion into yellow fatty marrow as a result of marrow ischemia
  • Modic type III
    • T1: low signal
    • T2: low signal
    • represents subchondral bony sclerosis

History and etymology

Michael T Modic (fl. 2018) is an American neuroradiologist at the Vanderbilt University Medical Center in Nashville, Tennessee, in the US, although almost the whole of his career prior to 2018 was spent at the Cleveland Clinic 3.

Share article

Article information

rID: 12146
Tag: cases, refs
Synonyms or Alternate Spellings:
  • Modic type end plate changes
  • Modic changes

Support Radiopaedia and see fewer ads

Cases and figures

  • Figure 1
    Drag here to reorder.
  • Modic type II : T1
    Case 1: Modic type II changes
    Drag here to reorder.
  • Case 2: Modic type I changes
    Drag here to reorder.
  • Updating… Please wait.

     Unable to process the form. Check for errors and try again.

     Thank you for updating your details.