Morgagni-Stewart-Morel syndrome consists of the triad of:
and is also associated with neuropsychiatric conditions. The cause is unclear.
History and etymology
It was first described in 1765 by the Italian anatomist and pathologist Giovanni Battista Morgagni (1682-1771) 2. The Scottish neuropsychiatrist Roy Mackenzie Stewart (1889-1964) 4 and the Swiss psychiatrist Ferdinand Morel (1888-1957) also contributed to the understanding of this condition 5. The latter is often confused with his namesake Benedict Augustin Morel (1809-1873), an Austrian psychiatrist, who was completely unrelated 6.
- 1. Smith S. and R. E. Hemphill. “HYPEROSTOSIS FRONTALIS INTERNA.” Journal of Neurology, Neurosurgery, and Psychiatry 19, no. 1 (February 1956): 42–45.
- 2. Zani A, Cozzi DA. Giovanni Battista Morgagni and his contribution to pediatric surgery. (2008) Journal of pediatric surgery. 43 (4): 729-33. doi:10.1016/j.jpedsurg.2007.12.065 - Pubmed
- 3. Attanasio F, Granziera S, Giantin V, Manzato E. Full penetrance of Morgagni-Stewart-Morel syndrome in a 75-year-old woman: case report and review of the literature. (2013) The Journal of clinical endocrinology and metabolism. 98 (2): 453-7. doi:10.1210/jc.2012-3242 - Pubmed
- 4. R M Stewart. Br Med J. 1964 Jun 13; 1(5397): 1572–1574.
- 5. de MONTMOLLIN. [Dr Ferdinand Morel, Geneva (1888-1957)]. (1959) Schweizer Archiv fur Neurologie, Neurochirurgie und Psychiatrie = Archives suisses de neurologie, neurochirurgie et de psychiatrie. 83: 342-4. Pubmed
- 6. Tsai SY. Eponym and identity. Benedict Augustin Morel (1809-1873) and Ferdinand Morel (1888-1957). (1968) Archives of general psychiatry. 19 (1): 104-9. Pubmed