Morning glory sign (midbrain)
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At the time the article was created Charlie Chia-Tsong Hsu had no recorded disclosures.View Charlie Chia-Tsong Hsu's current disclosures
At the time the article was last revised Daniel J Bell had no recorded disclosures.View Daniel J Bell's current disclosures
Graphically this is identified on an axial image at the level of the midbrain by drawing 1:
- a horizontal line drawn through the edge of the posterior cerebral aqueduct
- a second line is drawn along the lateral margin of the tegmentum from the intersection of the horizontal line to the "pit" between the tegmentum and the cerebral peduncle
In normal subjects the lateral margin of the tegmentum is convex and runs outside of this second line. However, in patients with progressive supranuclear palsy and multisystem atrophy with vertical supranuclear gaze-palsy the tegmentum is concave and the lateral margin runs inside the second line.
The morphology of the midbrain in patients with vertical supranuclear gaze-palsy resembles the morning glory flower thus termed the morning glory sign as originally described by Adachi et al 1.