MR arthrogram solution

Dr Henry Knipe and A.Prof Frank Gaillard et al.

An MR arthrogram solution is a dilute solution of gadolinium that is used in MR arthrography for injection into the joint prior to imaging. The joint injection is performed under fluoroscopic guidance. A number of recipes are used but a simple approach to preparing 20 mL of solution is as follows:

  • 10 mL normal saline
  • 0.1 mL gadolinium
  • 10 mL nonionic iodinated contrast

The amount of contrast used will depend on the joint. Other preparations include:

  • 5 ml solution made up of 0.1 mL gadolinium, 3.5 mL nonionic iodinated contrast, and 1.5 mL 1% lidocaine for shoulder and hip joint injections
  • 2.5 ml solution of 0.1 ml gadolinium and 2.5 ml nonionic iodinated contrast for wrist, elbow and ankle injections
  • adding lidocaine to the mixture can be done to relieve joint pain due to capsular distension, such pain may remains for 24 to 48 hours after injection
  • saline is added to dilute the gadolinium concentration if it is 0.5 (the usual concentration for IV injections), 5 ml of normal saline for 1 ml of 0.5 mL gadolinium

Other radiologists use the same mixture but with some modification in the volume of each component.

Alternatively intra-articular location can be confirmed with iodinated contrast in a separate syringe.

Note: avoid bubbles as they can be confused with intra-articular loose bodies.

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Article information

rID: 7268
Synonyms or Alternate Spellings:
  • MRI arthrogram solution
  • Arthrogram solution cocktail

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