MR spectroscopy in prostate cancer

MR spectroscopy is a promising development in the radiological evaluation of possible prostate malignancy

The MR spectroscopic evaluation is mainly based on the choline peak elevation and choline-creatinine ratios.

Choline/creatine to citrate ratios:

  • > 0.5: suspicious
  • > 0.8: very suspicious
  • > 2: abnormal

Additionally, the peak heights of citrate and choline can be compared visually2.

The addition of MR spectroscopic data to the conventional MRI has improved detection of prostate cancer and has also improved tumour volume detection, and staging capabilities of MRI.

Endorectal coils are considered superior to the body coils in the evaluation of prostate and periprostatic tissue imaging. With improving hardware and field strengths of MRI the surface array coils can also be used effectively in evaluating prostate.

The spectroscopic data can be superimposed on anatomical images and colour tumour maps can be obtained to depict the true tumour volume, this can be done in all three planes. Volumetric depiction is also possible.


Prostate pathology
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Article Information

rID: 6046
System: Urogenital
Synonyms or Alternate Spellings:
  • MR Spectroscopy in Ca Prostate

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