MRI contrast agents

Last revised by Dr Ammar Haouimi on 14 May 2021

MRI contrast agents have become an indispensable part of contemporary magnetic resonance imaging. Although MRI was initially hoped to provide a means of making definitive diagnoses without administering contrast media, it has been found that the addition of contrast agents in many cases improves sensitivity and/or specificity.

Paul Lauterbur and his associates were the first to demonstrate the feasibility of using paramagnetic contrast agents to improve tissue discrimination on MRI 1

Contrast agents can be grouped in many different ways. One way is to consider them according to the compartments in which they distribute. 

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