Mueller Weiss syndrome

Mueller Weiss syndrome refers to spontaneous multifactorial adult onset osteonecrosis of the tarsal navicular. This syndrome is distinct from Köhler disease, the osteochondrosis of the tarsal navicular bone that occurs in children.

It occurs in adults between 40 and 60 years of age and is more common in females. Patients present with mid- and hindfoot pain and pes planovarus.

Plain radiographic features can include

  • comma-shaped deformity due to collapse of the lateral part of the bone
  • medial or dorsal protrusion of a portion of the bone or the entire navicular bone

The disease may be bilateral or asymmetric and associated with pathologic fractures.

There is a radiographic staging.

  • can show oedema on STIR / PD FS images and is more sensitive in picking up the early changes due to its ability to detect marrow signal changes

The disease can be progressive at times, and it is associated with severe pain and disability. Initially, it is treated conservatively with analgesics and orthotics which if they fail then surgical treatment is considered.

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Article information

rID: 13429
Synonyms or Alternate Spellings:
  • Mueller-Weiss syndrome
  • Mueller-Weiss disease

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Cases and figures

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    right foot
    Case 1: Mueller-Weiss disease- bilateral
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    Case 2
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    Case 3
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    There is a collap...
    Case 4
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    Case 5: bilateral
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