Müllerian duct anomaly classification

Last revised by Mohammad Taghi Niknejad on 6 Dec 2022

The Müllerian duct anomaly classification is a seven-class system that can be used to describe a number of embryonic Müllerian duct anomalies:

  • class I: uterine agenesis/uterine hypoplasia
    • a: vaginal (uterus: normal/variety of abnormal forms)
    • b: cervical
    • c: fundal
    • d: tubal
    • e: combined
  • class II: unicornuate uterus/unicornis unicollis, ~15% (range 6-25%)
    • a: communicating contralateral rudimentary horn contains endometrium
    • b: non-communicating contralateral rudimentary horn contains endometrium
    • c: contralateral horn has no endometrial cavity
    • d: no horn
  • class III: uterus didelphys, ~7.5% (range 5-11%)
  • class IV: bicornuate uterus: 2nd most common type ~25% (range 10-39%)
    • a: complete division, all the way down to the external os (bicornuate bicollis)
    • b: partial division, not extending to the internal os (bicornuate unicollis)
  • class V: septate uterus: commonest anomaly, ~45% (range 34-55%)
    • a: complete division, all the way down to the internal or external os
    • b: incomplete division, involving the endometrial cavity but not the cervix
  • class VI: arcuate uterus, ~7%
  • class VII: in utero diethylstilbestrol (DES) exposure (T-shaped uterus)

See also

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Cases and figures

  • Figure 1: uterine anatomical abnormalities (illustrations)
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  • Case 1: uterine agenesis (class I)
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  • Case 2: uterus didelphys (class III)
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  • Case 3: uterus didelphys (class III)
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  • Case 4: bicornuate uterus (class IV)
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  • Case 5: septate uterus (class V)
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  • Case 6: arcuate uterus (class VI)
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  • Case 7: T-shaped uterus (class VII)
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  • Case 8: unicornuate uterus- Class II
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  • Case 9: uterine hypoplasia (class I)
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  • Case 10: uterine hypoplasia (class I)
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  • Case 11: Bicornuate uterus with triamniotic dichorionic triplet pregnancy (3D ultrasound)
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  • Case 12: complete septate uterus with duplicated cervix
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  • Case 13: partial bicornuate uterus with bilateral tubal block
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