Multicystic mesothelioma

Multicystic mesotheliomas are a rare benign subtype of mesothelioma commonly seen in young women. 

They are most common in young females. 

Patients generally present with non-specific symptoms such as abdominal or pelvic pain, or distension. A palpable abdominal or pelvic mass may eventually be felt on clinical examination. 

Typically comprises multiple grape-like clusters of cysts which are lined with mesothelium and separated by fibrous tissue components.

Primarily occurs in the pelvic peritoneum 2.

May appear as a multicystic pelvic mass 2,3.

  • typically seen as a well-defined low attenuating (cystic) pelvic mass
  • calcification is generally not a feature 

Can better delineate the pelvic cystic mass. Reported signal characteristics include:

  • T1: fluid components show low signal 
  • T2: fluid components show high signal
  • C+ (Gd): may show enhancement of septa

Surgery is the preferred option for localised lesions. The tumour tends to recur locally (25-50% of cases) 3,6. Not thought to be chemo- or radiosensitive 2. May respond to hormonal therapy 5.

The general differential includes:

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Article information

rID: 9143
System: Urogenital
Synonyms or Alternate Spellings:
  • Multicystic mesothelioma

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Cases and figures

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    Figure 1: gross pathology
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    Case 1: multicystic peritoneal mesothelioma
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