Multifocal glioblastoma
Multifocal glioblastomas are tumors which have multiple discrete areas of contrast-enhancing tumor embedded with, or connected by, T2/FLAIR signal abnormality. Multifocal glioblastomas are considered to be part of the one tumor and are commonly encountered, accounting for 2-20% of all glioblastomas 3,4.
Multifocal glioblastomas have been shown to have a poorer prognosis than solitary tumors 2,3.
Differential diagnosis
This is in contrast to multicentric glioblastomas, which have enhancing foci with normal intervening brain, and are thought to more likely represent synchronous but separate tumors.
Related Radiopaedia articles
Astrocytic tumour
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astrocytic tumors
- WHO classification of CNS tumors
- WHO grading of CNS tumors
- VASARI MRI feature set
- diffuse astrocytoma grading
- grade I:
- grade II:
- chordoid glioma of the third ventricle
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low-grade diffuse astrocytoma
- fibrillary astrocytoma (no longer recognized)
- protoplasmic astrocytoma (no longer recognized)
- gemistocytic astrocytoma
- oligoastrocytoma
- pilomyxoid astrocytoma
- pleomorphic xanthoastrocytoma
- grade III
- grade IV:
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glioblastoma (GBM)
- glioblastoma IDH wildtype
- glioblastoma IDH mutant
- glioblastoma NOS
- variants
- diffuse midline glioma H3 K27M–mutant
-
glioblastoma (GBM)
- glioblastoma vs cerebral metastasis
- radiation-induced gliomas
- gliomatosis cerebri (growth pattern)
- specific locations
- treatment response
- prognostic genetic markers