Multiple endocrine neoplasia type IIa

Last revised by Daniel J Bell on 04 Jun 2020

Multiple endocrine neoplasia (MEN) type IIa, also known as Sipple syndrome, accounts for most cases of MEN2 and is characterized by:

Mnemonic: 

  • PMP

Pathology

Genetics

A small proportion of individuals have a RET D631 proto-oncogene mutation.

See also

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Cases and figures

  • Case 1: pheochromocytoma
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