Multiple endocrine neoplasia type IIa

Multiple endocrine neoplasia (MEN) type IIa, also known as Sipple syndrome, accounts for most cases of MEN2 and is characterized by:

Mnemonic: 

  • PMP

Pathology

Genetics

A small proportion of individuals have a RET D631 proto-oncogene mutation.

See also

Article information

rID: 1621
System: Head & Neck
Section: Syndromes
Synonyms or Alternate Spellings:
  • MEN IIa
  • Multiple endocrine neoplasia type IIa
  • MEN 2a
  • Sipple syndrome

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Cases and figures

  • Case 1: pheochromocytoma
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