Musculoskeletal haemangiopericytoma

Dr Donna D'Souza et al.

Musculoskeletal haemangiopericytomas are now considered to be a cellular and more aggressive version of solitary fibrous tumours, and the term has largely been abandoned. 

These tumours are most frequently seen in middle-aged adults (~ 4th decade).


Typically they have large vessels especially located at its periphery, and commonly involve the lower limbs (35% of cases), especially the thigh, pelvis and retroperitoneum (25%). Primary osseous lesions are rare.

Radiologically they appear the same as angiosarcomas and haemangioendotheliomas.

Plain radiograph

Nonspecific soft tissue mass. When involving bone, they are predominantly lytic, and may mimic haemangiomas with a course honeycomb appearance.


Dense, well-circumscribed areas of enhancement with early draining veins and shunting. Hemangiopericytoma are described as having a pedicle formed by the arteries supplying the tumor from which vessels branch to encircle the tumor.


Nonspecific soft tissue mass, with a density similar to muscle but demonstrating bright contrast enhancement. CTA may demonstrate large feeding vessels.


Brightly enhancing soft tissue mass, often hyperintense on T2WI, with prominent flow voids, most marked in haemangiopericytomas.

Bone tumours

The differential diagnosis for bone tumours is dependent on the age of the patient, with a very different set of differentials for the paediatric patient.

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Article information

rID: 1418
Section: Pathology
Synonyms or Alternate Spellings:
  • Musculoskeletal haemangiopericytomas
  • Musculoskeletal hemangiopericytoma

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