Citation, DOI, disclosures and article data
Citation:
Weerakkody Y, Chieng R, Bell D, et al. Myelodysplastic/myeloproliferative neoplasms. Reference article, Radiopaedia.org (Accessed on 18 Apr 2024) https://doi.org/10.53347/rID-89389
Myelodysplastic syndrome / myeloproliferative neoplasm (MDS/MPN) overlap syndromes refer to a group of chronic clonal myeloid malignancies in which there are features of both myelodysplastic syndrome and myeloproliferative neoplasm at the time of presentation.
Entities that can fall into this group include 3:
chronic myelomonocytic leukemia
myelodysplastic/myeloproliferative neoplasm with neutrophilia
myelodysplastic/myeloproliferative neoplasm with SF3B1 mutation and thrombocytosis
myelodysplastic/myeloproliferative neoplasm, NOS
See also
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1. Pati H, Kundil Veetil K. Myelodysplastic Syndrome/Myeloproliferative Neoplasm (MDS/MPN) Overlap Syndromes: Molecular Pathogenetic Mechanisms and Their Implications. (2019) Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion. 35 (1): 3-11. doi:10.1007/s12288-019-01084-y - Pubmed
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2. Hunter AM, Padron E. Molecular genetics of MDS/MPN overlap syndromes. (2020) Best practice & research. Clinical haematology. 33 (3): 101195. doi:10.1016/j.beha.2020.101195 - Pubmed
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3. Cree I. The WHO Classification of Haematolymphoid Tumours. Leukemia. 2022;36(7):1701-2. doi:10.1038/s41375-022-01625-x - Pubmed
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