Myelomeningocele, also known as spina bifida cystica, is a complex congenital spinal anomaly that results in spinal cord malformation (myelodysplasia). 

It is one of the commonest congenital CNS anomalies and thought to occur in approximately 1:500 of live births 5. There may be a slight female predilection.

Patients present with lower limb paralysis and sensory loss, bladder and bowel dysfunction as well as cognitive impairment.

Results from failure of fusion of neural tube dorsally during embryogenesis. 

There is a localized defect of the closure of caudal neuropore with persistence of neural placode (open spinal cord).

  • lumbosacral: ~45%
  • thoracolumbar: ~30% 
  • lumbar: ~20%
  • cervical: ~2% 
  • may show evidence of an open neural tube defect with splayed or divergent posterior elements

Article information

rID: 5791
Synonyms or Alternate Spellings:
  • Myelomeningocele
  • Meningomyelocoele
  • Meningomyelocoele
  • Myelomeningocoeles
  • Myelomeningoceles
  • Meningomyelocoeles
  • Meningomyeloceles

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Cases and figures

  • Case 1: associated Chiari II
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  • Case 2
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  • Case 3
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  • Case 4: on antenatal ultrasound
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  • Case 5
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  • Case 6
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  • Case 7: on post natal ultrasound
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  • Case 8: upper dorsal myelomeningocele
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