Myxoid uterine leiomyoma

Myxoid uterine leiomyoma is a relatively rare pathological subtype of uterine leiomyomas. It is not to be confused with myxoid degeneration of a uterine leiomyoma which as a related but no identical meaning.

Myxoid leiomyomas contain abundant myxoid material between smooth muscle cells. The lesions are soft and translucent but solid. Large lesions may be clinically malignant even if they do not meet standard criteria for the diagnosis of sarcoma. In these lesions, smooth muscle cells are so widely separated by abundant myxoid material that mitotic count and cellularity cannot be assessed precisely 1

Pelvic MRI

Signal characteristics of the myxoid portion include

  • T1: geographic and variable signal dependant on protein content 5
  • T2: has high signal intensity 
  • T1 C+ (Gd)
    • enhances well except for small foci of mucinous lakes or clefts.
    • delayed and prolonged enhancement is seen due to the presence of a myxoid stroma.
Share article

Article Information

rID: 17643
System: Gynaecology
Tag: cases
Synonyms or Alternate Spellings:
  • Myxoid uterine leiomyomas
  • Myxoid uterine fibroid

Support Radiopaedia and see fewer ads

Updating… Please wait.
Loadinganimation

Alert accept

Error Unable to process the form. Check for errors and try again.

Alert accept Thank you for updating your details.