Myxoid uterine leiomyoma
Citation, DOI, disclosures and article data
At the time the article was created Yuranga Weerakkody had no recorded disclosures.View Yuranga Weerakkody's current disclosures
At the time the article was last revised Bruno Di Muzio had no recorded disclosures.View Bruno Di Muzio's current disclosures
Myxoid uterine leiomyomas are a relatively rare pathological subtype of uterine leiomyomas.
They are not to be confused with myxoid degeneration of a uterine leiomyoma which is a different entity.
Myxoid leiomyomas contain abundant myxoid material between smooth muscle cells. The lesions are soft and translucent but solid. Large lesions may be clinically malignant even if they do not meet standard criteria for the diagnosis of sarcoma. In these lesions, smooth muscle cells are so widely separated by an abundant myxoid material that mitotic count and cellularity cannot be assessed precisely 1.
Signal characteristics of the myxoid portion include:
- T1: geographic and variable signal dependent on protein content 5
- T2: high signal intensity
T1 C+ (Gd)
- enhances well except for small foci of mucinous lakes or clefts
- delayed and prolonged enhancement is seen due to the presence of a myxoid stroma
- MRI features can overlap with that of a uterine leiomyosarcoma 5
- 1. Ueda H, Togashi K, Konishi I et-al. Unusual appearances of uterine leiomyomas: MR imaging findings and their histopathologic backgrounds. Radiographics. 1999;19 Spec No : S131-45. Radiographics (full text) - Pubmed citation
- 2. Cruz M, Murakami T, Tsuda K et-al. Myxoid leiomyoma of the uterus: CT and MRI features. Abdom Imaging. 26 (1): 98-101. Abdom Imaging (link) - Pubmed citation
- 3. Sternberg SS. Diagnostic surgical pathology. Philadelphia : Lippincott Williams & Wilkins, c1999. (1999) ISBN:0397587929. Read it at Google Books - Find it at Amazon
- 4. Dähnert W. Radiology Review Manual. Lippincott Williams & Wilkins. (2011) ISBN:1609139437. Read it at Google Books - Find it at Amazon
- 5. Brant WE, Lange EE. Essentials of Body MRI. Oxford University Press, USA. (2012) ISBN:0199738491. Read it at Google Books - Find it at Amazon