N-acetylaspartate (NAA) peak

Dr Craig Hacking and A.Prof Frank Gaillard et al.

N-acetylaspartate (NAA) is one of the more important compounds assessed on MR spectroscopy, and resonates at 2.0 ppm chemical shift. 

NAA is the acetylated form of the amino acid, aspartate, which is found in high concentrations in neurons and is a marker of neuronal viability. It is therefore reduced in any process that destroys neurons, such as high grade tumours, radionecrosis, non-neuronal tumours (e.g. cerebral metastases and primary CNS lymphoma).

MR spectroscopy
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Article information

rID: 27827
Section: Physics
Tags: stub, refs
Synonyms or Alternate Spellings:
  • N-acetylaspartate peak
  • N-acetylaspartate (NAA)
  • NAA

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