N-acetylaspartate (NAA) peak

N-acetylaspartate (NAA) is one of the more important compounds assessed on MR spectroscopy, and resonates at 2.0 ppm chemical shift (its concentration in healthy adults is 8-10 mM) 1.

NAA is the acetylated form of the amino acid, aspartate, which is found in high concentrations in neurons and is a marker of neuronal viability. It is therefore reduced in any process that destroys neurons, such as high grade tumors, radionecrosis, non-neuronal tumors (e.g. cerebral metastases and primary CNS lymphoma).

MR spectroscopy
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Article information

rID: 27827
Section: Physics
Tag: stub, stub, refs
Synonyms or Alternate Spellings:
  • N-acetylaspartate peak
  • N-acetylaspartate (NAA)

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