Nabothian cyst

Nabothian cysts, also known as a retention cysts of the cervix 11, are non-neoplastic cystic lesions that occur in relation to the uterine cervix.

They are common and some reports suggest that they may be seen in up to 12% of routine pelvic MRI scans 2.

The majority are asymptomatic, although in rare cases they can enlarge and become symptomatic 12.

They are thought to form as a result of the healing process of chronic cervicitis and represent mucinous cysts due to obstruction from overgrowth of squamous epithelium. 

Symptomatic Nabothian cysts can also occur as a late complication of subtotal hysterectomy, in which internalisation of the transformation zone and partial obliteration of the canal are postulated as predisposing factors.

Nabothian cysts are usually small spanning a few millimetres in diameter but on occasion, have been reported reach extreme sizes of up to 4 cm.

Tunnel cluster: a special type of Nabothian cyst, is characterised by complex multicystic dilatation of the endocervical glands 

Typically seen an anechoic well defined cystic lesions near the endocervical canal. If the cysts are large, the cervical region can appear enlarged 11. Colour Doppler interrogation shows no associated colour flow.

If small may not be detectable on CT. May occasionally be seen a focal low attenuation regions within the cervical region.

They may be seen as well circumscribed single or multiple cystic lesions within the cervical stroma.

Signal characteristics typically follow that of fluid 2.

  • T1  
    • iso- to hypointense relative to muscle in typical cases
    • very rare cases with mucin may show some high signal
  • T2: cysts are hyperintense relative to muscle
  • T1 C+ (Gd): there is no associated enhancement

Most Nabothian cysts are clinically insignificant. The majority of cases are not treated because the cysts are entirely benign; however, an excision biopsy is sometimes indicated in large, complex, cystic lesions to rule out rare forms of mucus-producing neoplasia, including adenoma malignum 12

General imaging differential considerations include:

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Article information

rID: 13330
System: Gynaecology
Tag: cases
Synonyms or Alternate Spellings:
  • Nabothian cysts
  • Retention cyst of the cervix
  • Retention cysts of the cervix
  • Retention cyst of cervix
  • Cervical Nabothian cysts

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