The napkin ring sign may refer to either of the following imaging findings:
napkin ring sign (colon): colonic stenosis such as due to colon cancer
napkin ring sign (coronary): coronary artery vulnerable plaque
A clinical napkin ring sign of myotonia (e.g. in myotonic dystrophy) also exists, whereby striking the tongue elicits a characteristic pattern of contractions 1.
A napkin ring is a decorative household item used in some Western societies to hold cloth napkins in a roll at its center. The imaging metaphor applies to circumferential stenotic lesions.