Neonatal neuroblastoma is a type of congenital neuroblastoma, an embryonal tumor arising from the sympathetic nervous system. In the majority of cases (45%), the tumor is localized in the adrenal gland.
Epidemiology
Neonatal neuroblastoma accounts for less than 5% of all cases and carries a favorable prognosis, with most cases being low/intermediate risk for metastatic disease and recurrence.
Clinical presentation
Around 20% of neonatal neuroblastomas present with spinal cord compression due to intraspinal tumor extension.
Catecholamines are within normal limits or only slightly elevated in cases of neonatal neuroblastoma.
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