Neoplasms of the appendix

There are a number of neoplasms that can involve the appendix, some of which are peculiar to this site.


Tumours involving the appendix have been found in only about 1% of all appendectomy 9. Epithelial neoplasms and neuroendocrine tumours represent the gross majority of the tumours affecting the caecal appendix

Clinical presentation

Symptoms may vary from patients being completely asymptomatic, such as in small benign neuroendocrine tumours, to a clinical picture of acute appendicitis, which is reported in ~40% of cases and most commonly seen associated with neuroendocrine tumours 9

Mucinous neoplasms can lead to abdominal pain, gastrointestinal obstruction, and abdominal distension when evolving to a pseudomyxoma peritonei

Carcinoid syndrome related to malignant neuroendocrine tumours is rare, present in less than 5% of patients with this tumour. 

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Article information

rID: 20480
Section: Gamuts
Tag: stub
Synonyms or Alternate Spellings:
  • Appendiceal malignancies
  • Tumours of the appendix
  • Appendiceal neoplasms
  • Appendiceal tumours
  • Appendiceal tumors
  • Appendiceal malignancy
  • Appendiceal neoplasm

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Cases and figures

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    Case 1: mucinous cysdadenoma of appendix
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    Case 2: mucinous cystadenoma of appendix
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    Case 3: low grade mucinous neoplasm of the appendix
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