Neurofibrillary tangles

Dr Dan J Bell and A.Prof Frank Gaillard et al.

Neurofibrillary tangles (NFTs) are abnormal cytoplasmic accumulations of tau proteins, found in neuronal and glial cells of the central nervous system. They are responsible for a number of neurodegenerative diseases (collectively known as tauopathies) including 1:

Neurofibrillary tangles are also a prominent feature of Alzheimer disease, which in addition demonstrates extracellular neuritic plaques.

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Article information

rID: 13022
Section: Pathology
Synonyms or Alternate Spellings:
  • NFTs
  • NFT

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Cases and figures

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    Diagram : neurofibrillary tangle formation
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