Neurofibrillary tangles
Last revised by Daniel J Bell on 28 Apr 2020
Citation, DOI, disclosures and article data
Citation:
Gaillard F, Bell D, Sharma R, et al. Neurofibrillary tangles. Reference article, Radiopaedia.org (Accessed on 20 Sep 2024) https://doi.org/10.53347/rID-13022
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rID:
13022
Article created:
Disclosures:
At the time the article was created Frank Gaillard had no recorded disclosures.
View Frank Gaillard's current disclosures
Last revised:
28 Apr 2020,
Daniel J Bell ◉
Disclosures:
At the time the article was last revised Daniel J Bell had no recorded disclosures.
View Daniel J Bell's current disclosures
Revisions:
5 times, by
4 contributors -
see full revision history and disclosures
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Synonyms:
- Neurofibrillary tangles (NFTs)
Neurofibrillary tangles (NFTs) are abnormal cytoplasmic accumulations of tau proteins, found in neuronal and glial cells of the central nervous system. They are responsible for a number of neurodegenerative diseases (collectively known as tauopathies) including 1:
Neurofibrillary tangles are also a prominent feature of Alzheimer disease, which in addition demonstrates extracellular neuritic plaques.
References
- 1. Kornienko VN, Pronin IN. Diagnostic Neuroradiology. Springer Verlag. (2008) ISBN:3540756523. Read it at Google Books - Find it at Amazon
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