Nipple adenoma

Nipple adenoma is a rare, benign breast lesion which often mimics a malignancy

Patient presents with bloody discharge from an ulcerated and painful nipple in one breast. There is itching associated with this lesion. Symptoms may show variation with the menstrual cycle. There may enlargement of nipple and sometimes a mass may be palpated.

Can occur in any age group but most often seen in the age group of 40-50 years. It is seen in both females and males (<5%).

Gross pathology

A well circumscribed and unencapsulated lesion.

Microscopic

Glands with stromal fibrosis and epithelial hyperplasia.

Mammogram

Usually small in size lesions, which are not picked up on ultrasound. If seen they are seen as indistinct mass in the region of nipple.

Ultrasound

Mostly seen as a small (0.5 -1.5 cm),  well-circumscribed nodule in the superficial part of the nipple with homogeneous echogenicity. On doppler these lesions are hypervascular. Doppler sonography may also aid in diagnosis, since most of these entities are hypervascular. 

It is believed to be a premalignant lesion. Complete excision with a narrow rim of uninvolved breast tissue is adequate treatment.

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Article information

rID: 28590
System: Breast
Section: Pathology
Tag: breast
Synonyms or Alternate Spellings:
  • Florid papillomatosis of the nipple
  • Florid benign proliferation of nipple ductal epithelium
  • Erosive adenomatosis of the nipple
  • Florid papillomatosis of the nipple ducts
  • Nipple duct adenoma
  • Papillary adenoma of the nipple
  • Nipple adenomas

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