Nipple adenoma

Last revised by Patrick J Rock on 13 May 2021

Nipple adenoma is a rare, benign breast lesion which often mimics a malignancy

Patient presents with bloody discharge from an ulcerated and painful nipple in one breast. There is itching associated with this lesion. Symptoms may show variation with the menstrual cycle. There may be enlargement of the nipple and sometimes a mass may be palpated.

Can occur in any age group but most often seen in the age group of 40-50 years. It is seen in both females and males (<5%).

A well circumscribed and unencapsulated lesion.

Glands with stromal fibrosis and epithelial hyperplasia.

Usually small in size lesions, which are not picked up on ultrasound. If seen they are seen as an indistinct mass in the region of the nipple.

Mostly seen as a small (0.5 -1.5 cm),  well-circumscribed nodule in the superficial part of the nipple with homogeneous echogenicity. On Doppler these lesions are hypervascular. Doppler sonography may also aid in diagnosis since most of these entities are hypervascular. 

It is believed to be a premalignant lesion. Complete excision with a narrow rim of uninvolved breast tissue is adequate treatment.

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