Nodular filling defects due to mucosal lesions in the duodenum are due to a number of processes. For a differential list which includes non-mucosal lesions see duodenal filling defects.
The differential diagnosis for mucosal lesions includes:
-
heterotopic gastric mucosa
- 1-2 mm
- clustered
- only slightly elevated
-
benign lymphoid hyperplasia
- 1-2 mm
- discrete nodules
- diffusely scattered through the duodenal bulb
- seen in patients with decreased immunity
-
Brunner gland hyperplasia
- >1 cm
- diffusely scattered through the duodenal bulb
- cobblestone appearance
- smooth
- Peutz-Jeghers syndrome
- Cronkhite-Canada syndrome
- familial adenomatous polyposis (FAP)