Non-neoplastic solid lesions of the pancreas

Non-neoplastic solid lesions of the pancreas (NNSLP) are conditions which may mimic pancreatic neoplasms on imaging. They include:

  • focal pancreatitis
  • fatty infiltration-replacement
  • intrapancreatic accessory spleen
  • congenital anomalies, such as prominent pancreatic lobulations and bifid pancreatic tail (pancreatic bifidum)
  • miscellaneous rare conditions
    • pancreatic sarcoidosis
    • pancreatic Castleman disease (this is a lymphoproliferative condition may not strictly classify as a non neoplastic disease)

About 5% of pancreatectomies performed with the preoperative diagnosis of malignancies will prove to be non-neoplastic by pathologic examination; however, this figure is decreasing with the current state-of-the-art pancreatic imaging modalities 2

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Article information

rID: 38775
Section: Gamuts
Tags: stub, refs
Synonyms or Alternate Spellings:
  • Non-neoplastic solid lesions of the pancreas (NNSLP)
  • Non-neoplastic pancreartic solid lesions

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