Nothnagel syndrome

Dr Henry Knipe and Rohit Sharma et al.

Nothnagel syndrome is a rare midbrain stroke syndrome that involves the tectum of the midbrain, including the quadrigeminal plate 1-4. Although it can be caused by stroke, especially haemorrhages rather than infarctions, it is more commonly seen due to neoplasm 1-4. Classically, the syndrome involves the oculomotor nerve fascicles and superior cerebellar peduncle, leading to ipsilateral CN III palsy and limb ataxia respectively 1-4.   

History and etymology

The syndrome was first described by Hermann Nothnagel (1841-1905), a German-Austrian physician, in 1879 5.

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Article information

rID: 54279
Section: Syndromes
Synonyms or Alternate Spellings:
  • Nothnagel's syndrome

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