Odontogenic myxoma

Last revised by Thomas Tattersfield on 9 Oct 2022

Odontogenic myxomas are rare tumors that involve the mandible or maxilla and account for 3-6% of odontogenic tumors 2.

Typically seen in the 2nd to 3rd decades of life (slightly earlier than ameloblastomas). They are usually not painful.

Arises from mesenchymal odontogenic tissue.

The radiographic appearance is very similar to that of an ameloblastoma: a "soap bubble"-appearing lytic septated cystic lesion of the mandible.

Wide marginal excision is the treatment of choice. Local recurrence is possible.

It is thought to have been first described by Thoma and Goldman in 1947 6.

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