OEIS complex

Last revised by Bahman Rasuli on 24 Nov 2020

The OEIS complex refers to the combined occurrence of:


The estimated occurrence is at around 1-200,000 to 400,000 live births 1,8.


Possible embryologic mechanisms proposed for these findings include 7

  • a single defect of early blastogenesis or 
  • a defect of mesodermal migration during the primitive streak period

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