Esophageal squamous papilloma

Last revised by Daniel J Bell on 19 Mar 2019

Esophageal squamous papilloma is an uncommon finding on esophagography (barium swallow). It is a benign lesion, but it is difficult to differentiate it from osophageal carcinoma on esophagography and the diagnosis is usually made with endoscopic biopsy.

Clinical presentation

Often asymptomatic, but may cause dysphagia 2.


Benign hyperplastic epithelial lesion consisting of a fibrovascular core with multiple small projections.

Radiographic features

Barium oesophagram (barium swallow)
  • small sessile polyp with a smooth or slightly lobulated contour 3

Differential diagnosis

ADVERTISEMENT: Supporters see fewer/no ads

Cases and figures

  • Photo 1: H&E stain
    Drag here to reorder.