Okuda staging system

Last revised by Dr Matt A. Morgan on 16 Jun 2015

The Okuda staging system was an advance on earlier hepatocellular (HCC) staging classifications, in that it incorporated both cancer-related variables and liver function related variables to determine prognosis 1:

  • disease involving >50% of hepatic parenchyma
  • ascites
  • albumin ≤3 mg/dL
  • bilirubin ≥3 mg/dL

These are combined into stages:

  • stage A: 0 criteria
  • stage B: 1-2 criteria
  • stage C: 3-4 criteria

Higher stages were correlated with a poorer prognosis.

History and etymology

The staging classification was published by K Okuda et al in 1985.

See also

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