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At the time the article was created Henry Knipe had no recorded disclosures.View Henry Knipe's current disclosures
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Oligometastases, or oligometastatic disease, refers to distant disease that is limited in number and distribution. Niibe et al. defined this as ≤5 metastatic/recurrent lesions with control of the primary lesion 1,2. Also, the definition states a maximum of three different metastatic sites 3.
These metastases can be treated with local measures (surgery, radiation therapy, thermal ablation, etc.) with the aim of increasing survival. This is a shift from traditional thinking where metastatic disease was considered an end-stage disease with limited palliative treatment options only.
- 1. Niibe Y, Hayakawa K. Oligometastases and oligo-recurrence: the new era of cancer therapy. Jpn. J. Clin. Oncol. 2010;40 (2): 107-11. doi:10.1093/jjco/hyp167 - Free text at pubmed - Pubmed citation
- 2. Huang F, Wu G, Yang K. Oligometastasis and oligo-recurrence: more than a mirage. Radiat Oncol. 2014;9 (1): 230. doi:10.1186/s13014-014-0230-6 - Free text at pubmed - Pubmed citation
- 3. Van Cutsem E, Cervantes A, Adam R, Sobrero A, Van Krieken JH, Aderka D, Aranda Aguilar E, Bardelli A, Benson A, Bodoky G, Ciardiello F, D'Hoore A, Diaz-Rubio E, Douillard JY, Ducreux M, Falcone A, Grothey A, Gruenberger T, Haustermans K, Heinemann V, Hoff P, Köhne CH, Labianca R, Laurent-Puig P, Ma B, Maughan T, Muro K, Normanno N, Österlund P, Oyen WJ, Papamichael D, Pentheroudakis G, Pfeiffer P, Price TJ, Punt C, Ricke J, Roth A, Salazar R, Scheithauer W, Schmoll HJ, Tabernero J, Taïeb J, Tejpar S, Wasan H, Yoshino T, Zaanan A, Arnold D. ESMO consensus guidelines for the management of patients with metastatic colorectal cancer. (2016) Annals of oncology : official journal of the European Society for Medical Oncology. 27 (8): 1386-422. doi:10.1093/annonc/mdw235 - Pubmed