Last revised by Dr Bálint Botz on 01 Nov 2020

Oligometastases, or oligometastatic disease, refers to distant disease that is limited in number and distribution. Niibe et al. defined this as ≤5 metastatic/recurrent lesions with control of the primary lesion 1,2. Also, the definition states a maximum of three different metastatic sites 3

These metastases can be treated with local measures (surgery, radiation therapy, thermal ablation, etc.) with the aim of increasing survival. This is a shift from traditional thinking where metastatic disease was considered an end-stage disease with limited palliative treatment options only.

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Cases and figures

  • Fig 1. oligo- and polymetastatic disease
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