OnyxTM is the trade name for a liquid embolic agent used in interventional radiology for the occlusion of blood vessels in embolization therapy. It is an elastic copolymer (ethylene vinyl alcohol copolymer (EVOH)), dissolved in dimethyl-sulfoxide (DMSO). Micronised tantalum powder is also added as an ingredient to provide radiopacity.
It comes in two strengths:
- Onyx 18: 6% ethylene vinyl alcohol
- Onyx 34: 8% ethylene vinyl alcohol
History and etymology
It was first described by Taki et al. in 1990 4.
- 1. van Rooij WJ, Sluzewski M, Beute GN. Brain AVM embolization with Onyx. AJNR Am J Neuroradiol. 2007;28 (1): 172-7. AJNR Am J Neuroradiol (full text) - Pubmed citation
- 2. Guimaraes M, Wooster M. Onyx (Ethylene-vinyl Alcohol Copolymer) in Peripheral Applications. Semin Intervent Radiol. 2011;28 (03): 350-6. doi:10.1055/s-0031-1284462 - Free text at pubmed - Pubmed citation
- 3. Saraf R, Shrivastava M, Kumar N et-al. Embolization of cranial dural arteriovenous fistulae with ONYX: Indications, techniques, and outcomes. Indian J Radiol Imaging. 2010;20 (1): 26-33. doi:10.4103/0971-3026.59748 - Free text at pubmed - Pubmed citation
- 4. Taki W, Yonekawa Y, Iwata H et-al. A new liquid material for embolization of arteriovenous malformations. AJNR Am J Neuroradiol. 1990;11 (1): 163-8. Pubmed citation