Ossifying fibromyxoid tumour (OFMT) is a soft tissue tumour of uncertain lineage.
It typically manifests in adults. There may be a slight increased male predilection.
The clinical presentation can vary depending on location but usually tends to manifest as a slowly growing painless mass.
Its exact aetiology is not very clear but a schwannian or chondroid origin has sometimes been favoured. It comprises of small round cells dispersed in a myxoid matrix and can contain bone, osteoid, and collagen elements.
It is reported to most often arise in the subcutaneous extremities.
Other reported locations include
Treatment and prognosis
It is generally considered benign although recurrence following the resection can be common. Complete local resection is considered the best treatment in many cases.
- 1. Ideta S, Nishio J, Aoki M et-al. Imaging findings of ossifying fibromyxoid tumor with histopathological correlation: A case report. Oncol Lett. 2013;5 (4): 1301-1304. doi:10.3892/ol.2013.1170 - Free text at pubmed - Pubmed citation
- 2. Blum A, Back W, Naim R et-al. Ossifying fibromyxoid tumor of the nasal septum. Auris Nasus Larynx. 2006;33 (3): 325-7. doi:10.1016/j.anl.2006.01.008 - Pubmed citation
- 3. Al-Mazrou KA, Mansoor A, Payne M et-al. Ossifying fibromyxoid tumor of the ethmoid sinus in a newborn: report of a case and literature review. Int. J. Pediatr. Otorhinolaryngol. 2004;68 (2): 225-30. Pubmed citation
- 4. Shetty SD, Salib RJ, Nair SB et-al. Ossifying fibromyxoid tumour of the sphenoid sinus. J Laryngol Otol. 2010;124 (04): 437-40. doi:10.1017/S0022215109991289 - Pubmed citation
- 5. Cha JH, Kwon JW, Cho EY et-al. Ossifying fibromyxoid tumor invading the spine: a case report and review of the literature. Skeletal Radiol. 2008;37 (12): 1137-40. doi:10.1007/s00256-008-0562-0 - Pubmed citation
- 6. Tateishi U, Gladish GW, Kusumoto M et-al. Chest wall tumors: radiologic findings and pathologic correlation: part 1. Benign tumors. Radiographics. 2003;23 (6): 1477-90. doi:10.1148/rg.236015526 - Pubmed citation
- 7. Petscavage-Thomas JM, Walker EA, Logie CI et-al. Soft-tissue myxomatous lesions: review of salient imaging features with pathologic comparison. Radiographics. 2014;34 (4): 964-80. doi:10.1148/rg.344130110 - Pubmed citation
- 8. Choi JH, Park JS, Jin W et-al. Sonographic features of an ossifying fibromyxoid tumor of the buttock. J Ultrasound Med. 2008;27 (5): 809-12. J Ultrasound Med (full text) - Pubmed citation