Ossifying fibromyxoid tumour

Dr Henry Knipe and Dr Yuranga Weerakkody et al.

Ossifying fibromyxoid tumour (OFMT) is a soft tissue tumour of uncertain lineage.

It typically manifests in adults. There may be a slight increased male predilection.

The clinical presentation can vary dependent on location but usually tends to manifest as a slowly growing painless mass.

Its exact aetiology is not very clear but a schwannian or chondroid origin has sometimes been favoured. It comprises of small round cells dispersed in a myxoid matrix and can contain bone, osteoid, and collagen elements.

It is reported to most often arise in the subcutaneous extremities.

Other reported locations include

It is generally considered benign although recurrence following resection can be common. Complete local resection is considered the best treatment in many cases.

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Article information

rID: 36876
Section: Pathology
Synonyms or Alternate Spellings:
  • Ossifying fibromyxoid tumours
  • Ossifying fibromyxoid tumor
  • Ossifying fibromyxoid tumors
  • Ossifying fibromyxoid tumor (OFMT)
  • Ossifying fibromyxoid tumour (OFMT)
  • Ossifying fibromyxoid tumour (OFT)
  • Ossifying fibromyxoid tumor (OFT)

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