Ossifying fibromyxoid tumor

Ossifying fibromyxoid tumors are soft tissue tumors of uncertain lineage.

Epidemiology

It typically manifests in adults. There may be a slight increased male predilection.

Clinical presentation

The clinical presentation can vary depending on location but usually tends to manifest as a slowly growing painless mass.

Pathology

Its exact etiology is not clear but a schwannian or chondroid origin has sometimes been favored. It comprises of small round cells dispersed in a myxoid matrix and can contain bone, osteoid, and collagen elements.

Location

It is reported to most often arise in the subcutaneous extremities. Other reported locations include

• ribs / chest wall ⁶
• nasal septum ²
• sinuses
  • ethmoid sinus ³
  • sphenoid sinus ⁴

Treatment and prognosis

It is generally considered benign although recurrence following the resection can be common. Complete local resection is considered the best treatment in many cases.

See also

• soft tissue tumors (classification) - WHO 2002