Ossifying renal tumor of infancy

Last revised by Pir Abdul Ahad Aziz Qureshi on 27 Jul 2022

Ossifying renal tumor of infancy (ORTI) is a rare renal tumor.

  • extremely rare, <<1% of pediatric renal neoplasms (17 cases reported)
  • 6 days - 3 months
  • male predominant

Histology reveals spindle cells and osteoblastic cells in a calcified osteoid matrix. It is thought to originate from intralobar nephrogenic rests.

  • calcification is hyperechoic
  • there may be intra-tumoral flow on color Doppler ultrasound

ORTI may resemble a staghorn calculus since it originates from the renal papilla, but it enhances postcontrast.

Cases of ORTI so far have been benign, with no recurrence after resection.

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