Osteomas are benign mature bony growths, seen almost exclusively in bones formed in membrane (e.g. skull).
When they arise from bone they may be referred to as a "homoplastic osteoma", and when they arise in soft tissue they may be referred to as a "heteroplastic osteoma".
These lesions are benign, slow growing, and usually asymptomatic. They may be incidentally identified as a mass in the skull or mandible, or as the underlying cause of sinusitis or mucocele formation within the paranasal sinuses. When they are multiple, Gardner syndrome should be considered.
They commonly occur in the head and neck, with the most common locations including:
paranasal sinus osteoma
- ivory osteoma seen most commonly in this location
- skull vault osteoma
- mandibular osteoma
- nasal bones 4
Osteomas are, as the name suggests, osteogenic tumors composed of mature bone. Three histological patterns are recognized 1:
- also known as eburnated osteoma
- dense bone lacking Haversian system
- also known as osteoma spongiosum
- resembles 'normal' bone, including trabecular bone often with marrow
- a mixture of ivory and mature histology
The imaging appearance reflects the underlying pathology, with ivory osteomas appearing as very radiodense lesions, similar to the normal cortex, whereas mature osteomas may demonstrate central marrow.
Treatment and prognosis
Osteomas are benign and only require excision if they cause adjacent complications (e.g. mucocele formation) or mass-effect (functional or cosmetic impairment).
- 1. Maroldi R, Nicolai P, Antonelli AR. Imaging in treatment planning for sinonasal diseases. Springer Verlag. (2005) ISBN:3540423834. Read it at Google Books - Find it at Amazon
- 2. Erdogan N, Demir U, Songu M et-al. A prospective study of paranasal sinus osteomas in 1,889 cases: changing patterns of localization. Laryngoscope. 2009;119 (12): 2355-9. Laryngoscope (full text) - doi:10.1002/lary.20646 - Pubmed citation
- 3. Wenig BM. Atlas Of Head And Neck Pathology. Saunders. (2008) ISBN:0721697887. Read it at Google Books - Find it at Amazon
- 4. Wolfgang Dähnert. Radiology Review Manual. (2011) ISBN: 9781609139438
Related Radiopaedia articles
The differential diagnosis for bone tumors is dependent on the age of the patient, with a very different set of differentials for the pediatric patient.
- bone-forming tumors
- cartilage-forming tumors
- bizarre parosteal osteochondromatous proliferation (Nora lesion)
- chondromyxoid fibroma
- juxtacortical chondroma
- fibrous bone lesions
- bone marrow tumors
- other bone tumors or tumor-like lesions
- aneurysmal bone cyst
- benign fibrous histiocytoma
- giant cell tumor of bone
- Gorham massive osteolysis
- haemophilic pseudotumor
- intradiploic epidermoid cyst
- intraosseous lipoma
- musculoskeletal angiosarcoma
- musculoskeletal hemangiopericytoma
- primary intraosseous hemangioma
- post-traumatic cystic bone lesion
- simple bone cyst
- impending fracture risk
- describing a bone lesion