Osteonecrosis of the humeral head

Last revised by Arlene Campos on 11 Jan 2024

Osteonecrosis of the humeral head, also known as Haas disease, is considered the second most common location for osteonecrosis (following the hip). 

Insidious onset of pain poorly localized and usually severe night and rest. The range of motion is initially preserved. In the later stages a "click" can accompany some movements from joint incongruity, cartilage flap, or a large loose body.

It generally develops in the subchondral region. In some patients, osteonecrosis can lead to the collapse of the necrotic subchondral bone, the development of an irregular joint surface, and subsequent joint degeneration. 

There are many causes of humeral head osteonecrosis; the most frequent are:

  • trauma: fracture, fracture-dislocations

  • sickle-cell anemia

  • metabolic: Gaucher disease

  • rheumatologic disorders: systemic lupus erythematosus

  • extrinsic factors: dysbaric conditions (Caisson disease)

  • alcohol consumption

  • iatrogenic

  • corticosteroids

    • recognized as a dominant causative association

    • corticosteroids cause fat accumulation in the marrow, leading to increased intraosseous hypertension and decreased blood flow

  • organ transplantation

Osteonecrosis of the humeral head is staged using the Cruess classification 6.

AP, Grashey, axillary and Y projections are typically performed.

Radiographs will be normal in early disease. The most common initial site is the upper middle portion of the humeral head. Early shoulder osteonecrosis shows cystic and/or sclerotic changes in the humeral head.

The presence of a crescent sign is the classic diagnostic feature that in the correct clinical context demonstrates subchondral collapse. This may progress to depression of the articular surface with subsequent arthritic changes.

MRI is the preferred imaging modality. The diagnosis of osteonecrosis on MRI is based on band-like abnormal signals:

  • T1: low signal serpiginous line demarcating the osteonecrosis

  • T2: double line sign (inner bright line from granulation tissue and outer dark line from sclerotic bone)

Conservative treatment such as pain medication and physical therapy can be performed for milder cases. Operative procedures include core decompression, shoulder hemiarthroplasty or total shoulder arthroplasty for more severe cases, in particular:

Dysbaric shoulder osteonecrosis was reported as early as 1911 by Bornstein and Plate. In 1960, Heimann and Freiberger publish the first descriptions of osteonecrosis of the shoulder.

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