Ovarian embryonal carcinoma

Last revised by Dr Bahman Rasuli on 24 Nov 2020

Ovarian embryonal carcinomas are rare and malignant germ cell tumors of the ovary.

It is found predominantly in children and adolescents (average age 14 years).

Precocious puberty or menstrual irregularity occurs in 60% 2. The tumor can secrete beta-hCG and/or AFP

Pure embryonal carcinoma is rare and embryonal carcinoma often occurs mixed with other malignant germ cell tumor types.

Predominantly solid, but nonspecific imaging features on ultrasound, CT, and MRI, that overlap with other germ cell tumors 3. Abnormal serum markers in the setting of an adolescent with a unilateral solid ovarian mass would put the tumor on a differential diagnosis.

For this malignant tumor, staging laparotomy and salpingo-oophorectomy is an accepted treatment, followed by chemotherapy.

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