Ovarian fibrosarcoma

Ovarian fibrosarcoma is a malignant mesenchymal fibroblastic tumour of the ovary that have multiple mitotic figures which is most important factor in histopathological diagnosis (4 or more mitotic figure per 10 high power fields). 

Ovarian fibrosarcoma are very rare malignant ovarian tumours, usually seen in peri- or post-menopausal women. 

Ovarian fibrosarcoma is a a unique fibrous tumour with high mitotic figures arise from the ovary. It can be de novo or arise from an ovarian fibroma as malignant transformation.

A large unilateral ovarian heterogeneous solid mass which frequently has areas of haemorrhage and or cystic degeneration. It may extends beyond boundaries of the ovary.

Ovarian fibrosarcoma has a poor prognosis and treatment consists of complete surgical resection followed by chemotherapy.

Poor prognostic factors are very high mitotic figure, necrosis and less collagen.

Consider other unilateral ovarian tumours.

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Article information

rID: 44502
System: Gynaecology
Section: Pathology
Tags: cases, stub
Synonyms or Alternate Spellings:
  • Ovarian fibrosarcomas

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