Ovarian mucinous cystadenocarcinoma

Dr Craig Hacking and Radswiki et al.

Mucinous cystadenocarcinoma of the ovary is a rare malignant ovarian mucinous tumour. This type can account for 5-10% of all ovarian mucinous tumours. It is a type of ovarian epithelial tumour

Retrospective studies have suggested that many mucinous carcinomas initially diagnosed as primary to the ovary have in fact metastasised from another site 4.

  • a development of mucinous cystadenocarcinoma has been very rarely associated with malignant transformation of a mature cystic teratoma 1

In general, the cell type (e.g. serous, mucinous) often cannot be determined on the basis of appearance at MR imaging, CT, or ultrasound 6. Biopsy or excision is necessary.

A mucinous ovarian carcinoma is less likely to be bilateral than serous carcinoma, with bilateral lesions occurring in 5-10% of the stage I cases. 

Mucinous tumors are typically multilocular, with numerous smooth, thin-walled cysts. Mucoid material is found within the cysts, sometimes accompanied by haemorrhagic or cellular debris. A proportionately greater solid, nonfatty, non-fibrous tissue is often considered the most powerful predictor of malignancy 6.

CT may demonstrate high attenuation in some loculi due to the high protein content of the mucoid material

  • T1
    • the signal intensity of mucin on T1-weighted images varies depending on the degree of mucin concentration
    • on T1-weighted images, loculi with watery mucin have a lower signal intensity than loculi with thicker mucin. 
  • T2
    • on T2-weighted images, the corresponding signal intensities are flipped, so that loculi with watery mucin have high signal intensity and loculi with thicker mucin appear slightly hypointense.

The staging is the same as general ovarian cancer staging.

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Ultrasound - gynaecology
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Article information

rID: 15100
System: Gynaecology
Synonyms or Alternate Spellings:
  • Ovarian mucinous cystadenocarcinoma
  • Mucinous cystadenocarcinoma of the ovary
  • Mucinous ovarian cysadenocarcinoma
  • Primary mucinous cystadenocarcinoma of ovary
  • Mucinous cystadenocarcinoma of ovary

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