Ovarian mucinous cystadenocarcinoma

Mucinous cystadenocarcinoma of the ovary is a rare malignant ovarian mucinous tumor. This type can account for 5-10% of all ovarian mucinous tumors. It is a type of ovarian epithelial tumor

Retrospective studies have suggested that many mucinous carcinomas initially diagnosed as primary to the ovary have in fact metastasised from another site 4.

  • a development of mucinous cystadenocarcinoma has been very rarely associated with malignant transformation of a mature cystic teratoma 1

In general, the cell type (e.g. serous, mucinous) often cannot be determined on the basis of appearance at MR imaging, CT, or ultrasound 6. Biopsy or excision is necessary.

A mucinous ovarian carcinoma is less likely to be bilateral than serous carcinoma, with bilateral lesions occurring in 5-10% of the stage I cases. 

Mucinous tumors are typically multilocular, with numerous smooth, thin-walled cysts. Mucoid material is found within the cysts, sometimes accompanied by hemorrhagic or cellular debris. A proportionately greater solid, nonfatty, non-fibrous tissue is often considered the most powerful predictor of malignancy 6.

CT may demonstrate high attenuation in some loculi due to the high protein content of the mucoid material

  • T1
    • the signal intensity of mucin on T1-weighted images varies depending on the degree of mucin concentration
    • on T1-weighted images, loculi with watery mucin have a lower signal intensity than loculi with thicker mucin
  • T2
    • on T2-weighted images, the corresponding signal intensities are flipped, so that loculi with watery mucin have a high signal intensity and loculi with thicker mucin appear slightly hypointense

The staging is the same as general ovarian cancer staging.

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Ultrasound - gynaecology
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Article information

rID: 15100
System: Gynaecology
Synonyms or Alternate Spellings:
  • Ovarian mucinous cystadenocarcinoma
  • Mucinous cystadenocarcinoma of the ovary
  • Mucinous ovarian cysadenocarcinoma
  • Primary mucinous cystadenocarcinoma of ovary
  • Mucinous cystadenocarcinoma of ovary

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