Pancoast syndrome (historically known as Ciuffini-Pancoast-Tobías syndrome, Hare syndrome or variation thereof) results from involvement of the brachial plexus and sympathetic chain by a Pancoast tumor or, less commonly, from other tumors - or even non-malignant disease - involving the lung apex.
The syndrome consists of:
- shoulder pain
- C8-T2 radicular pain
- Horner syndrome
The classical syndrome is uncommon, with Horner syndrome present in only 25%.
History and etymology
Pancoast syndrome as a result of apical lung tumors was described in a number of publications (by Hare in 1838, Ciuffini in 1911 and Tobias in 1932) before Pancoast reported it using the term 'superior pulmonary sulcus tumor' 2-4.
- Edward Selleck Hare (1812-1838), British physician
Publio Ciuffini (18??-19??), Italian physician
- Ciuffini, is mentioned in non-referenced sources 2, an original reference remains elusive
- Henry Khunrath Pancoast (1875-1939), American radiologist, Philadelphia
- Jose W Tobias, Argentine physician, Buenos Aires 4
- 1. Webb WR, Higgins CB. Thoracic imaging. Lippincott Williams & Wilkins. ISBN:078174119X. Read it at Google Books - Find it at Amazon
- 2. Pancoast's syndrome from whonamedit.com, the dictionary of medical eponyms. Pancoast's syndrome
- 3. Pancoast HK. Importance of careful roentgen-ray investigation of apical chest tumors. (1924) Journal of the American Medical Association. 83 (18): 1407. doi:10.1001/jama.1924.02660180025007
- 4. Tobías JW (1931). Sindrome ápico-costo-vertebral doloroso por tumor apexiano: su valor diagnóstico en el cáncer primitivo pulmonar (Doctoral dissertation). Revista medica Latino-americana, Buenos Aires, 1932, 17: 1522-1557