Pancreatic atrophy

Last revised by Dr Jeremy Jones on 20 Sep 2021

Pancreatic atrophy is non-specific and is common in elderly patients, although in younger patients it can be a hallmark of pathology. Most commonly it is associated with aging, obesity and end-stage chronic pancreatitis

It occurs principally with fatty replacement of the pancreas (pancreatic lipomatosis), and the etiology overlaps considerably. 

Lobular (lobulocentric) atrophy may be seen in pancreatic malignancies including

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Cases and figures

  • Case 1: chronic pancreatitis
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  • Case 2: cystic fibrosis
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