Pancreatic intraepithelial neoplasia

Dr Bruno Di Muzio and Dr Henry Knipe et al.

Pancreatic intraepithelial neoplasia (PanIN) is a precursor lesion to pancreatic ductal adenocarcinoma, but the frequency at which this transition occurs is unknown. 


Increasing incidence with age 1. Risk factors:


More commonly located in the pancreatic head 1

Radiographic features

May produce unifocal or multifocal lobulocentric pancreatic atrophy but a preoperative diagnosis of PanIN is extremely difficult as it is a microscopic lesion 2,4

Pancreatic pathology
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Article information

rID: 35510
Section: Pathology
Tag: cases
Synonyms or Alternate Spellings:
  • Pancreatic intraepithelial neoplasia (PanIN)
  • Pancreatic intraepithelial neoplasias

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