Pancreatic mesenchymal neoplasms

Last revised by Bruno Di Muzio on 11 Feb 2024

Pancreatic mesenchymal neoplasms, or pancreatic nonepithelial neoplasms, are a group of rare pancreatic neoplasms that arise from the structural elements of the pancreas (nerves, fat, lymph), rather than from the exocrine or endocrine cells of the pancreas. Neoplasms from exocrine and endocrine cells result in more familiar pancreatic neoplasms such as pancreatic ductal adenocarcinoma, IPMN, and pancreatic endocrine tumours (formerly termed "islet cell tumours").

Pancreatic mesenchymal neoplasms are rare and represent at most 1-2% of pancreatic neoplasms 2.

Pancreatic nonepithelial tumours can be broadly divided into those that are benign and those that are malignant.

A disparate group of tumours, they have many different imaging appearances, based on their underlying histology. As a group, these neoplasms tend to better-marginated than the more infiltrative pancreatic ductal adenocarcinoma 1.

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