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At the time the article was created Marcos Gil Alberto da Veiga had no recorded disclosures.View Marcos Gil Alberto da Veiga's current disclosures
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Pandystrophies are neurological diseases that demonstrate both white and grey-matter involvement, as opposed to leukodystrophies (dominated by white matter involvement) or poliodystrophies (dominated by grey matter involvement).
Most metabolic diseases with central nervous system involvement fall into this category, as exclusively white or gray matter involvement is quite uncommon.
In fact, a grey matter neuroimaging abnormality can be caused by myelin breakdown, and a white matter neuroimaging abnormality can be a reflexion of secondary neuronal degeneration.