Papillary cystadenomas are usually asymptomatic.
They are more common in young men (20-40 years) 2. Approximately 30% of patients have vHL and ~35% (range 10-60%) of patients with vHL have papillary cystadenoma(s) 1,2.
Lesions are usually arising from the head of the epididymis and can present as a cystic lesion with a thick wall and several peripheral solid nodules with increased vascularity, partially or completely cystic or solid lesion and measuring up to 3 cm in diameter 1.
Patients with bilateral papillary cystadenomas of the epididymis should be considered for vHL screening 2.
- 1. Toutziaris C, Kampantais S, Perdikis I et-al. Papillary cystadenoma of epididymis: Is there a need for further investigation in unilateral cases?. Int J Surg Case Rep. 2013;4 (7): 616-8. doi:10.1016/j.ijscr.2013.03.038 - Free text at pubmed - Pubmed citation
- 2. Ganeshan D, Menias CO, Pickhardt PJ, Sandrasegaran K, Lubner MG, Ramalingam P, Bhalla S. Tumors in von Hippel-Lindau Syndrome: From Head to Toe-Comprehensive State-of-the-Art Review. (2018) Radiographics : a review publication of the Radiological Society of North America, Inc. 38 (3): 849-866. doi:10.1148/rg.2018170156 - Pubmed